منابع مشابه
Immunoglobulins in Nzb/bl Mice
Determination of serum immunoglobulin levels in NZB and normal mice has indicated that an elevation of the gammaM-globulin level occurs in NZB mice. This can be demonstrated in young NZB mice well before other autoimmune manifestations are observed. A slight elevation of gammaM-globulin was also observed in NZB hybrid mice. Erythrocyte autoantibodies were analyzed by the direct Coombs' test wit...
متن کاملThe Immunoglobulins of Mice
Two classes of 7S gamma-globulins are identified in normal mouse serum and are designated 7S gamma(2)-globulins and 7S gamma(1)-globulins. These two immunoglobulin classes are similar in size. They differ in range of electrophoretic mobility, in specific antigenic determinants, and in genetically determined isoantigens. Four classes of immunoglobulins in mouse serum, i.e. 7S gamma(2)-, 7S gamma...
متن کاملImmunoglobulins of Mice
Studies in man (1, 2), rabbit (3), and guinea pig (4) have shown that the 18S 71-macroglobu]ins (IgM) are catabolized much more rapidly than 7S 72-globulins (IgG). Thus, immunoglobulin classes may differ in their rates of turnover. Differences in the catabolic control of immunoglobulins are also discernable. The serum level of 7S 7-globulin (IgG) helps to determine the catabolic rate; the highe...
متن کاملInvestigation of secretory immunoglobulins in saliva from germfree mice.
We investigated the effect of oral immunization on the serum and salivary immunoglobulin levels in axenic and conventional NIH mice. Specific antibacterial and antifungal antibodies were measured by passive hemagglutination, and differences in the immunoglobulin classes were measured by radial immunodiffusion. After an oral immunization regimen with either intact Escherichia coli or Candida alb...
متن کاملImmunoglobulins of Mice V . the Metabolic ( Catabolic ) Properties of Five
Studies in man (1, 2), rabbit (3), and guinea pig (4) have shown that the 18S 71-macroglobu]ins (IgM) are catabolized much more rapidly than 7S 72-globulins (IgG). Thus, immunoglobulin classes may differ in their rates of turnover. Differences in the catabolic control of immunoglobulins are also discernable. The serum level of 7S 7-globulin (IgG) helps to determine the catabolic rate; the highe...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1968
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.127.1.169